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Nerve Imaging and Surgery: Photonics West 2022 Preview
Iatrogenic nerve injury represents one of the most feared surgical complications and remains a major morbidity across all surgical specialties. No clinically approved technology can enhance intraoperative nerve visualization, typically performed through neuroanatomical knowledge and conventional white light visualization alone. However, nerves are difficult or impossible to identify by white light visualization and neuroanatomy is often varied between patients

Presenters of top-rated talks in Photonics West BiOS will give updates on their research addressing this problem. Moderator Sylvain Gioux (Intuitive Surgical) will facilitate discussion with the speakers and the audience at the conclusion of the presentations.

"Can Near Infrared Nerve-Specific Fluorophores Improve Surgical Outcomes?"
Summer Gibbs (Oregon Health & Science Univ.)

We have developed near infrared nerve-specific small-molecule fluorophores compatible with the existing fluorescence guided surgery clinical infrastructure. We are currently working towards clinical translation of this novel technology to aid in nerve identification and visualization in the operating room.

"Multimodal intrinsic contrast imaging for intraoperative nerve visualization“
Graham Throckmorton (Vanderbilt Univ.)

We combine diffuse reflectance and polarization imaging techniques to visualize nerves in vivo based on their biochemical composition and structural organization. Both modalities successfully localized nerves within the field of view in an in vivo rat model while tissue optical property measurements revealed underlying sources of contrast. The results of this study provide valuable insight into the future development of a real-time clinical imaging system.

Oct 19, 2021 08:00 AM in Pacific Time (US and Canada)

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